In the News
(May 2015 Volume 39 Number 5) - Pharmaceutical Technology (PharmTech.com) - "Evaluating Disinfectant Efficacy of a Silver-Based Disinfectant," by John M. Lindsay
A disinfectant composed of a low-concentration suspension of silver ions is a quick-acting sporicidal disinfectant that is non-corrosive, is skin-safe (non-toxic), and is not a respiratory irritant. The disinfectant was evaluated at the Aseptic Training Institute (ATI) at the Johnston Community College Work Force Development Center in Clayton, NC. Six microbial preparations were used as challenge organisms for the disinfectant on four different surface materials. In addition, the effectiveness of the disinfectant was evaluated in situ by collecting environmental samples after intentionally contaminating and cleaning a facility and equipment. The author reports the results of these evaluations and concludes that the disinfectant is completely sporicidal with only a one-minute contact time. Click here to view the entire article in .pdf format.
(October 2014) - "Determining Facility Mold Infection," by Jim E. Akers and John M. Lindsay
Consistent mold presence at high recovery levels indicates facility infection. With the publicity surrounding the recovery of mold from pharmacy compounding facilities and formulated products connected to patient fungal infections and deaths, there has been a heightened awareness and concern for fungal recoveries in all manufacturing facilities. One comment often heard is that the presence of bacteria in a drug or biological manufacturing facility is expected, because these microorganisms are constituents of normal human flora, but the presence of mold in such facilities is presumed to be atypical as fungi are not considered constituents of human flora. Molds, however, are often found on healthy human skin and associated with hair. At any given point in time, humans may carry dermatophytic molds typically of the genera Trichtophyton, Microsporum, or Epiderophyton. Although mold are not present in or on humans in the numbers that bacteria are, they certainly can be found. Click here to view the entire article in .pdf format.
(September 2014) STERIPLEX HC Receives EPA Registration (click here to see a Powerpoint Presentation delivered by John Lindsay, Aseptic Training)
STERIPLEX HC is a revolutionary new Sterilant/Sporicide, which has recently received Federal EPA Registration. A paradigm shift in infection control STERIPLEX HC sets new standards, killing spores in a tiny fraction of the time of competing products. Independent GLP certified laboratories have verified that STERIPLEX HC destroys the most virulent pathogens including C. sporogenes and B. subtilis spores 10 to 32 times faster than other sterilant brands. With never before seen kill times, these results are truly remarkable as virulent spores are truly some of the toughest germs to kill. A sporicide will typically destroy all other germ species as well.
STERIPLEX HC is completely non-corrosive, non-flammable and 100% biodegradable. STERIPLEX HC can be used as a semi-critical care instrument sterilant and to disinfect all hard surfaces. Competing sterilants have performance problems and/or serious corrosion and toxic side effects. Because of many adverse side effects, a commonly used sporicide was banned in Great Britain several years ago. Chlorine-based products are extremely corrosive and harmful if inhaled or swallowed. Alcohol-based products, which offer only modest antimicrobial performance, disintegrate plastics and are harmful if inhaled or swallowed.
Now consider that the new spore testing benchmarks required by the EPA to achieve sterilant (sporicidal) registration are far more rigorous today than the testing required of previously approved chemical sporicides. The new EPA spore testing protocols required STERIPLEX HC to be tested against spore concentrations of nominally 100 times previous testing levels. Even so, STERIPLEX HC passed all testing in record times. EPA Registration #84545-5 was issued to sBioMed November 2, 2009. STERIPLEX HC is registered as a broad spectrum Sterilant/Sporicide, Tuberculocide, and Bactericide.
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